About the TRN
Across scientific fields, there is growing interest in the utilization of telomere length (TL) as a sentinel of the environmental exposome and psychosocial stress across the life course, and as a predictor of mortality, aging-related health outcomes, and health span. Although TL is a primary hallmark of aging and is linked to disease risk and exposure in meta-analytic studies, inconsistencies across studies and procedures hamper our ability to test fundamental mechanisms and interactive models. Despite these limitations, the value of telomere research is significant, as meta analytic findings have confirmed relationships between TL and all-cause mortality, depression, schizophrenia, cardiovascular disease, as well as presumed precursors including air pollution and early life stress. The Telomere Research Network will emphasize synergistic research that capitalizes on existing networks and infrastructure, accessible cohorts, and expertise across diverse disciplines including aging, stress, environmental exposure, development, and biostatistics.
Goals of the TRN:
- Create a diverse and interactive network of invested stakeholders in the telomere field
- Investigate methodologic concerns in telomere length metrics and other telomere indicators and facilitate interactive discussions focused on best practice for TL measurement in population studies
- Develop infrastructure for cross-disciplinary dialogue, dissemination, and research related to telomere length as a sentinel of exposure and a predictor of health and aging